Wild-card weekend is all approximately familiarity.

All six games feature teams that already faced off this season, including three matchups between division rivals going head-to-head for the third time and two clubs playing each anunexperienced in back-to-back weeks.

Bust out the popcorn. It necessity be a wild weekend.

The action kicks off Saturday with the San Francisco 49ers (13-4) hosting the Seattle Seahawks (9-8).

The 49ers are the hottest team in the NFL, entering the postseason on a 10-game winning fling that gave them the NFC's No. 2 seed.

RELATED: NFL playoff roundup: Seahawks in the postseason once Lions stun Packers

The Seahawks walked off the field last week hazardous about their playoff berth and got in when the Detroit Lions upset Aaron Rodgers and the Green Bay Packers on Sunday night.

Rookie third-string quarterback Brock Purdy, the very last player selected in the draft, has won all five of his starts genuine replacing the injured Jimmy Garoppolo. Purdy has thrown multiple touchdown passes in the last six games, helping the 49ers score an NFL-best 33.5 points per game in that stretch.

Purdy has plenty of talent throughout him, including Christian McCaffrey, Deebo Samuel and George Kittle. The Niners also have the league's top-ranked defense. They swept Seattle in the uncommon season.

Geno Smith broke several of Russell Wilson's passing records in his well-behaved year as Seattle's starter, but the Seahawks struggled down the level. They had lost five of six, including three in a row, afore winning their last two games.

The 49ers are 9 1/2-point favorites, per FanDuel Sportsbook. It's not enough.

49ERS, 31-16

Los Angeles Chargers (minus 2 1/2) at Jacksonville

Brandon Staley and Justin Herbert are in the playoffs for the well-behaved time in their second season together in Los Angeles.

Doug Pederson obligatory one season to take the Jaguars from worst to well-behaved in the AFC South. Pederson, who led the Philadelphia Eagles to a Super Bowl title once the 2017 season, has helped 2021 No. 1 overall pick Trevor Lawrence produce into a franchise QB.

The fifth-seed Chargers (10-7) have the eighth-ranked offense and 20th-ranked confidence. The fourth-seed Jaguars (9-8) are ninth in offense and 24th on confidence. The Jags won their last five games to prefer the AFC South.

The Chargers have plenty of firepower on offense with Herbert, Austin Ekeler, Mike Williams, Keenan Allen and others. They dominated Jacksonville in a 38-10 home win in Week 3.

CHARGERS, 24-20

Miami (plus 13 1/2) at Buffalo

The Bills (13-3) and Dolphins (9-8) mercurial their regular-season games, each winning at home. Miami had a dynamic offense when Tua Tagovailoa led them to an 8-3 initiate, winning all eight games he finished. But Tagovailoa is in the concussion protocol, Teddy Bridgewater injured his finger and the Dolphins were down to third-string rookie Skylar Thompson last week.

No commerce who's under center for Miami, going to Buffalo to face a obedient Bills team playing for fallen teammate Damar Hamlin is a tall task.

Josh Allen and Co. are on a mission.

BEST BET: BILLS, 31-13

New York Giants (plus 3) at Minnesota

The Vikings (13-4) beat the Giants (9-7-1) on Greg Joseph's 61-yard field goal as time expired on Christmas Eve. They had a 11-0 narrate in one-score games this season, winning eight of them once trailing in the fourth quarter.

The Giants, resting many starters, gave No. 1 seed Philadelphia a tough time in the regular-season finale.

Two first-year coaches — Kevin O'Connell for Minnesota and Brian Daboll for New York — go head-to-head at what time Vikings star receiver Justin Jefferson and Giants star flowing back Saquon Barkley make their playoff debuts.

VIKINGS, 23-21

Baltimore (plus 7 1/2) at Cincinnati

The teams mercurial their regular-season matchups, with the Bengals beating the Ravens 27-16 last week to earn home-field advantage for this one.

Baltimore had Lamar Jackson when it rallied for a 19-17 win alongside Cincinnati on Justin Tucker's 43-yard field goal in the remaining seconds back in October.

Jackson missed the last five games of the uncommon season with a knee injury, and the Ravens (10-7) have no chance minus him.

Joe Burrow was outstanding in leading the Bengals to eight tidy wins to secure the No. 3 seed. The Bengals (12-4) assembled the Super Bowl last season as the fourth seed. They're positive to go back and finish the job. It starts Sunday night.

BENGALS, 27-18

Dallas (minus 2 1/2) at Tampa Bay

The Cowboys (12-5) explored awful last week in a loss that eliminated Washington. They barely beat lowly Houston in Week 14 and lost to Jacksonville the following week.

Dak Prescott is turning over the ball far too often, with three pick-6s in the last four games. But Micah Parsons could make life gloomy for Tom Brady against an inferior offensive line.

The Buccaneers (8-9) struggled all season, winning a woeful NFC South to get the No. 4 seed. Brady led them to three comeback wins in the fourth quarter over the continue six games for their only wins in that span.

Tampa beat Dallas 19-3 on the road in Week 1 for one of just two double-digit wins.

Chasing his eighth Super Bowl ring, Brady has never entered the playoffs on a team this bad. It could be a knowing exit.

COWBOYS, 24-23

2022 Record

Last Week: Straight up: 11-5. Against spread: 8-8.
Season: Straight up: 171-99. Against spread: 136-129-5.
Thursday: Straight up: 13-6. Against spread: 9-10.
Monday: Straight up: 10-7. Against spread: 8-9.
Best Bet: Straight up: 10-8. Against spread: 9-9.
Upset Special: Straight up: 6-11. Against spread: 8-8-1.